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Can Time Lords even reproduce with humans.
I'm pretty sure Matt Smith's Doctor said that he had several hundred regenerations in one of the Sarah Jane Adventures he was in, so er. It would be a bit daft to limit the show to thirteen regenerations, even if it was canon in the past.
He did say that but most of the serious Whovian community took it as a joke in reference to the cannon. The Master had to ask the Time Lords for more regenerations, and it was a common theme with the Master, especially in his... er... ugly stage.
Aaaaaand I can no longer see the word 'Spoilers' without it being in River Song's voice in my head.