Sure, I play a few. I don't get a ton of opportunities but my extended family's pretty fond of them, and I'm trying to get into some tabletop RPG stuff but keep lazing around, oops. One of my cousins in particular is really, really into all sorts of games and so I've been exposed to a fair few things that he either has or that we've bought for him as gifts.
Settlers of Catan: Tried it once, couldn't get into it. Two of the other players were really, really good, and when I have to simultaneously pay attention to what the good players are doing and just learn the basics of the game in the first place I tend to zone out. It's not that I mind losing or learning from more experienced players, but it's kind of hard to enjoy a game while you are both confused and actively being curbstomped, you know? (Much more fun to learn a game when no one has any bloody idea what's going on, imo, so you can all laugh about how confused you are together! Plenty of time to learn the finer strategic details and ruthlessly destroy one another later.) That said, the setting and mechanics didn't quite click with me anyway, so I doubt I'd have been really excited about it even if my cousins had slowed down a little more.
Pandemic: Have not played it yet, although I do own it and would like to at least give it a shot. My cousin said it was just kind of okay, but I'm still curious.
Deckbuilders: Haven't played Dominion before, but I did play Ascension once and rather enjoyed it! I'd definitely be up for trying more deckbuilders if the opportunity arises.
Coup: Pretty good! Nice and quick, in contrast to most of the stuff we play, and a good way to wrap up a game night when you want to do just one more thing before everyone leaves. My brother and cousin have been particularly into it ever since I got it a while ago. I'm tempted to get the expansion for it.
Mafia and similar: So one year I made the mistake of introducing my family to Mafia, and now they badger me into bringing the cards I made to basically every gathering we have so I can sit back and listen to them yell at each other! They're normally so quiet and friendly and only get slightly competitive about games, but Mafia makes them all mean and shouty! They're not even particularly good at it; they're mostly just loud. I have created a monster, alas. I just wish that most of our gatherings included slightly more people—I don't actually mind running the games all that much but I'm getting tired of the standard cop-doc setup and would like to introduce more/different roles. In general, though, IRL Mafia-style games are great! Also I bought Resistance and we tried that a while ago; it went over well enough, so hopefully that can be used to break up the MAFIA MAFIA MAFIA MAFIA [KRATOS] DID YOU BRING MAFIA IT IS TIME FOR MAFIA every once in a while.
Cards Against Humanity/Apples to Apples: I've somehow managed to never play CAH! That's not the sort of thing my family would be into playing with me, and I miss most of my internet friends' calls for online games. I was never sure it would hold my interest for very long, though, so I'm glad to see I'm not missing much. I did try Apples to Apples one time at a Christmas party. It was pretty good, I guess!
TCGs: When I was a kid/teenager I was really big on Pokémon and Yu-Gi-Oh!, but I can't drum up much enthusiasm for TCGs these days. I've tried Magic on and off, but in spite of the fact that it seems like it'd hit all the right notes with me in terms of theme and strategy I just can't get into it (sorry, Negrek!). I used to want to create my own TCGs all the time, though! For a few years straight my Christmas lists included packs of cheap playing cards (so I could use them for proxies while testing) and I'm sure my poor family was so confused, bless them. I had ideas for original games and a Fire Emblem one and some kind of ridiculous "Nintendo TCG" that would've included characters and items from like every franchise, although of course the latter two were never going to happen outside my head, haha. Then again, I've never been good at TCGs in the first place—and what the hell do I know about actually balancing them—so realistically none of them were going to go anywhere. Ah, well, they were fun to dream up! I like imagining games of all sorts even if they never get made.
Tabletop RPGs: Only became interested in these recently! Negrek has heard me talk about trying to get into Pathfinder multiple times, although so far I don't have much to show for it other than playing a few Pathfinder Society sessions at the local con, which of course is only once a year, oops. (I just found out that the anime con my brother and cousin go to has some tabletop stuff, though? Hm, perhaps I can bump that up to a whopping twice a year...) I routinely forget the very basics of the game in between sessions! Sooo I really need to stay more on top of that, maybe find an online group that runs some Roll20 tables, actually get off my ass and try to make it to one of the PFS nights that's at a restaurant I think I can get to without a car. Soon! Eventually!
Speaking of, if anyone is considering trying D&D-style RPGs but isn't feeling up to campaigns that go on for weeks/months/years, Pathfinder Society consists entirely of sessions meant to be completed in one sitting! It doesn't require the same level of investment as a big campaign, and you don't have to play with the same people or characters every time if you don't want to/can't. Plus you can earn points to make your characters cooler I guess, but mostly I like the short games. I'm not averse to the idea of a big campaign and would like to try one sometime, but I think PFS's one-shots made the whole pen-and-paper muddle a lot easier to get into. Whether or not they have society play, I'm pretty sure most tabletop RPGs have one-shot adventures of some sort!
Some other popular(?) ones no one's mentioned afaict: My cousin also introduced me to Talisman, which is long but usually fun. I got the Steam version and fire it up every once in a while. Not recently, mind, not after the AI player locked me into a weird stalemate situation that dragged the game out for an additional hour before I could finally get through and win. I've also recently tried Save Doctor Lucky! Everyone was very confused while playing it but seemed to have a good time. I'd meant to get the original Kill Doctor Lucky (Save Doctor Lucky is technically a prequel) but it's currently(?) out of print. They have a free printable version of the original while they prepare for the next edition, though, so if I can assemble the pieces for it maybe we'll try that one next time.
And then yeah, you have the more "casual/traditional" board games like Clue and Balderdash and so on. Haven't done Monopoly in ages, although it's less because I think it's "all about luck" and more because everyone around here (including me) is just sick of it and hasn't managed to shake that burnout even after many years, haha.
tl;dr I've dabbled in a lot of games and most of them are pretty enjoyable, and I want to play more! In addition to Pandemic I've also got Smallworld sitting there as-yet-untested; my cousin keeps telling us about The Red Dragon Inn and saying it's pretty fun; and I have an app version of Carcassonne on my tablet, which I hear is supposed to be some sort of classic so I guess I should get around to trying it eventually!